ARTERIOSCLEROSIS DE MONCKEBERG PDF

Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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Clinical and laboratory findings excluded any kind of rheumatologic disease such as dermatomyositis, scleroderma or systemic lupus erythematosus. The concomitant atherosclerotic process involving the intima layer of the femoral arteries explained the intermittent claudication and weak pulses presented by this patient.

It has been described how the deposition of these nanocrystals is capable to induce a phenotypic plasticity of the mesenchymal cells derived from the vascular smooth muscle cells, leading them to a transdifferentiation both in vitro and in vivogaining osteogenic characteristics that are directly related with medial vascular calcification. This calcification is usually circumferential and may affect the vessel either focally or diffusely.

The first type is a benign, slowly progressive, essentially asymptomatic form with thin medial calcifications and little or no narrowing of the arterial lumen. It was created in December with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Probably it has been worsened by the concomitant left ventriculat disfunction.

See more Follow us: His hands and feet were warm with no evidence of limb ischaemia. Generally, the pathogenesis of upper airway obstruction involves anatomic and neurological components. Monckeberg’s sclerosis is a rare and low prevalence disease of unknown cause in which small and medium size arteries suffer calcification of the middle layer, leading to a reduction in caliber.

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BMC Cardiovasc Disord,pp. Popliteal artery rupture during total knee replacement in arteriosxlerosis patient with Monckeberg’s sclerosis. Although the use of calcium chelators such as sodium thiosulfate has been proposed, the few available studies have failed to show significant results. A vaginal hysterectomy with pelvic floor repair was done on December 9, Systemic vasculitis are serious and life-threatening pathologies, however, the heterogeneity of their clinical manifestations arteriossclerosis it difficult to establish an arteriosclerisis diagnosis.

We would like to report the occurrence of this sclerosis in uterine vessels in an utero-vaginal prolapse. From Wikipedia, the free encyclopedia. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Report of case and litera On physical examination, he had cold and edematous right lower limb, with absence of popliteal and distal pulses, marked pallor at limb elevation, moderate reactive hyperemia and venous filling time arteriosclerossis 45 seconds.

Her medical history was significant for intermittent claudication. Monckeberg’s sclerosis can be an unexpected contraindication to arterial puncture in patients planned for coronary angiography and percutaneous intervention. Support Center Support Center. Translumbar aortography mohckeberg near-total obstruction of the femoral arteries.

A neck X-ray and computed tomography evidenced grossly calcified areas of soft tissue in the topography of the pharynx and larynx.

The left lower limb was assessed using arterial Doppler ultrasound, which showed major parietal calcifications and occlusion of the anterior and posterior tibial, fibular and dorsalis pedis arteries.

Radiographic manifestations of Mönckeberg arteriosclerosis in the head and neck region

The exact pathogenic mechanism of medial calcinosis is not well understood. Nat Commun, 3pp. Ueber die reine Mediaverkalkung der Extremitaetenarterien und ihr Verhalten zur Arteriosklerose. Can J Ophthalmol, 48pp. Author information Copyright and License information Disclaimer.

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Monckeberg’s arteriosclerosis – Wikipedia

Best Pract Res Clin Rheumatol, 24pp. Treatment Percutaneous angioplasty was performed with drug eluting stents to the right coronary artery and the left anterior descending artery in a staged approach. The exact cause of the cardiac disfunction could not be widely investigated, but OSA is an important contributor.

It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. Calcium deposits form in the middle layer of the walls of medium-sized vessels, and these arteriosclerosiw become calcified independently of atherosclerosis. Argeriosclerosis calcification results from the deposition of calcium phosphate crystals hydroxyapatite as a consequence of disordered calcium phosphate regulation in the blood vessel.

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Specific measures for the treatment of Monckeberg’s sclerosis are not currently available, and only are taken measures aimed to optimize the calcium metabolism, including calcium chelators such as sodium thiosulfate. J Clin Endocrino Metab.

Her general condition was good. Hypertension Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension. Slices of vessels and smooth muscle cells of the middle layer, focally replaced by hyalinized fibrous tissue presenting concentric dystrophic calcification.

Right anterior oblique caudal view showing a normal left main coronary artery.

Radiographic manifestations of Mönckeberg arteriosclerosis in the head and neck region

However, it can occur in pseudoxanthoma elasticum and idiopathic arterial calcification of infancy as a pathological condition, as well. Coronary calcification in patients with chronic kidney disease and coronary artery disease. J Knee Surg ; Most patients with medial calcinosis are asymptomatic, and it is usually an incidental finding, arterioscleerosis either clinically or on panoramic or periapical radiographs.

Comparative histological study of atherosclerotic lesions and microvascular changes in amputated lower limbs of diabetic and non-diabetic patients. This type of calcification is most common in diabetics.

Views Read Edit View history. The arterioeclerosis report provides a new insight about this disease, i. Differentiation of multipotent vascular stem cells contributes to vascular diseases. Additionally, it worked as a treatment for osteoporosis presented by the patient. Kidney Int, 87pp. Chest X-ray revealed mild enlargement of cardiac area associated with ectasic thoracic aorta; pulmonary aspects were normal.